ea0078OC5.5 | Oral Communications 5 | BSPED2021
Peckham Hannah
, Rosser Elizabeth C
, Radziszewska Anna
, Robinson George
, Martin-Gutierrez Lucia
, De Gruijter Nina M
, Jury Elizabeth C
, Butler Gary E
, Ciurtin Coziana
Cis-gender females are known to mount stronger humoral immune responses than cis-gender males. Little is known about the immunophenotypes of transgender individuals on gender-affirming hormonal treatment, despite growing evidence that hormones influence the immune system.Via the process of class-switch recombination (CSR), B-cell immunoglobulin isotype ‘switches’ from early IgM/IgD classes to IgG/IgA/IgE. Whilst important in infection/vaccine responses; switched isot...